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GTP BINDING PROTEIN ALPHA SUBUNIT
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DeCS
Descriptor
English
:
GTP-Binding Protein alpha Subunits
Descriptor
Spanish
:
subunidades alfa de las proteínas de unión al GTP
Descriptor
Portuguese
:
Subunidades alfa de Proteínas de Ligação ao GTP
Synonyms
English
:
G Protein alpha Subunit
G-Protein alpha Subunit
GTP Binding Protein alpha Subunit
GTP Binding Protein alpha Subunits
GTP-Binding Protein alpha Subunit
alpha Subunit, G-Protein
Tree Number:
D08.811.277.040.330.300.200.100
D12.644.360.360.100
D12.776.157.325.332.100
D12.776.476.375.100
D12.776.543.325.100
Definition
English
:
The GTPase-containing subunits of
heterotrimeric GTP-binding proteins
. When dissociated from the heterotrimeric complex these subunits interact with a variety of
second messenger systems
.
Hydrolysis
of GTP by the inherent GTPase activity of the subunit causes it to revert to its inactive (heterotrimeric) form. The
GTP-Binding protein alpha subunits
are grouped into families according to the type of action they have on
second messenger systems.
History Note
English
:
2004; use HETEROTRIMERIC GTP-BINDING PROTEINS 2001-2003
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
38130
Unique Identifier:
D044385
Occurrence in VHL
:
Similar:
DeCS